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C22orf32 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983487
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50-198-3487 100 μL
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Catalog No. 50-198-3487 Supplier Bioss Supplier No. BS15136R
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Description

Rabbit Polyclonal Antibody

Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria (PubMed:24231807, PubMed:26774479, PubMed:27099988). Required to bridge the calcium-sensing proteins MICU1 and MICU2 with the calcium-conducting subunit MCU (PubMed:24231807). Plays a central role in regulating the uniplex complex response to intracellular calcium signaling (PubMed:27099988). Acts by mediating activation of MCU and retention of MICU1 to the MCU pore, in order to ensure tight regulation of the uniplex complex and appropriate responses to intracellular calcium signaling (PubMed:27099988).

Specifications

Antigen C22orf32
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SMDT1
Gene Accession No. Q9H4I9
Gene Symbols SMDT1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human C22orf32.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 91689
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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