Invitrogen™ C2orf60 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565020

Catalog No. PIPA565020

Description

Immunogen sequence: KRVVLFSPRDA QYLYLKGTKS EVLNIDNPDL AKYPLFSKAR RYECSLEAGD VLFIPALWFH NVISEEFGVG VNIFWKHLPS ECYDKTDTYG NKDPTAASRA AQILDRALKT LAELPEEYRD FYARRMV Highest antigen sequence identity to the following orthologs - mouse 90%, rat 89%.

tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.

Specifications

• Antigen: C2orf60
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TYW5
• Gene Alias: C2orf60; hTYW5; jmjC domain-containing protein C2orf60; tRNA wybutosine-synthesizing protein 5; tRNA yW-synthesizing enzyme 5; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase; tRNA-yW synthesizing protein 5; TYW5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 129450
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A2RUC4
• Gene Symbols: TYW5
• Immunogen: Recombinant Human C2orf60. Recombinant protein control fragment (Product #RP-89696).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG