C4 gamma chain Mouse anti-Human, Clone: 2G6A7, Proteintech

Catalog No.	Quantity
50-173-6675	150 μL

Catalog No. 50-173-6675 Supplier Proteintech Group Inc Supplier No. 662421IG150UL

Description

Mouse Monoclonal Antibody

This antibody raised against 1543-1744aa of human C4-A protein recognizes C4 gamma chain.

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.

Specifications

• Antigen: C4 gamma chain
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 2G6A7
• Concentration: 0.81 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: C4A
• Gene Accession No.: P0C0L4
• Gene Alias: Acidic complement C4, C4, C4A, C4A2, C4A3, C4A4, C4A6, C4S, CO4, Complement C4 A, CPAMD2, RG
• Gene Symbols: C4A
• Host Species: Mouse
• Immunogen: C4 gamma chain Fusion Protein Ag10449
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 720
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1