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C4B Mouse anti-Human, Clone: OTI1B2, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF813010

Encompass_Preferred

Catalog No. 50-167-1044


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.
Specifications

Specifications

C4B
Monoclonal
Unconjugated
C4B
C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CH, CO4, CPAMD3
Mouse
Affinity Chromatography
RUO
721
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI1B2
PBS with 8% trehalose and no preservative; pH 7.3
P0C0L5
C4B
Human recombit protein fragment corresponding to amino acids 1100-1350 of human C4B produced in E.coli.
100 μg
Primary
Human
Antibody
IgG2a
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