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C5R1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980795
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50-198-0795 100 μL
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Catalog No. 50-198-0795 Supplier Bioss Supplier No. BS10288R
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Description

Rabbit Polyclonal Antibody

CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract. CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production. CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex. Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.

Specifications

Antigen C5R1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene C5AR1
Gene Accession No. P21730
Gene Alias BOS_17624; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor-like; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5ar; C5a-R; C5AR1; C5R1; CD88; CD88 antigen; complement C5a receptor; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1; LOC100352978
Gene Symbols C5AR1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human C5R1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 728
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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