Invitrogen™ C6orf57 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA573014

Catalog No. PIPA573014

Description

C6orf57 Polyclonal Antibody for Western Blot

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416). Binds to the flavoprotein subunit Sdha in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit Sdhb into the SDH catalytic dimer.

Specifications

• Antigen: C6orf57
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SDHAF4
• Gene Alias: 1110058L19Rik; 1700001E18Rik; C6orf57; hypothetical protein LOC685888; LOC685888; SDH assembly factor 4; Sdh8; SDHAF4; Succinate dehydrogenase assembly factor 4, mitochondrial; succinate dehydrogenase complex assembly factor 4; UPF0369 protein C6orf57; UPF0369 protein C6orf57 homolog
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 68002
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide
• Gene Accession No.: Q8BTE0
• Gene Symbols: SDHAF4
• Immunogen: A portion of amino acids 75-129 of mouse UPF0369 protein C6orf57 homolog was used as the immunogen.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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