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C6orf57 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983601
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50-198-3601 100 μL
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Catalog No. 50-198-3601 Supplier Bioss Supplier No. BS15249R
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Rabbit Polyclonal Antibody

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954416). Binds to the flavoprotein subunit Sdha in its FAD-bound form, blocking the generation of excess reactive oxigen species (ROS) and facilitating its assembly with the iron-sulfur protein subunit Sdhb into the SDH catalytic dimer.

Specifications

Antigen C6orf57
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SDHAF4
Gene Accession No. Q5VUM1
Gene Alias 1110058L19Rik; 1700001E18Rik; C6orf57; SDH assembly factor 4; Sdh8; SDHAF4; Succinate dehydrogenase assembly factor 4, mitochondrial; succinate dehydrogenase complex assembly factor 4; UPF0369 protein C6orf57; UPF0369 protein C6orf57 homolog
Gene Symbols SDHAF4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human C6orf57.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 135154
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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