C8A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
FEPA5145448	Invitrogen™ PA5145448	20 μL
FEPA5145447	Invitrogen™ PA5145447	200 μL

Description

C8A is a component of the complement system and contains three polypeptide subunits: alpha, beta and gamma. C8A, in particular, contains the alpha subunit of C8 and is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Disease associated with C8A include Type 1 C8 deficiency and immunodeficiency due to C8A deficiency.

Specifications

• Antigen: C8A
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat
• Gene Alias: C8a; complement component 8 alpha subunit; complement component 8 subunit alpha; complement component 8, alpha polypeptide; complement component C8 alpha chain
• Gene Symbols: C8A
• Isotype: IgG
• Purification Method: Protein A
• Gene: C8A

• Concentration: 0.5 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene ID (Entrez): 298288
• Immunogen: Recombinant Rat C8a protein, Gln21-His300 (Accession #D3ZWD6).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.