Invitrogen™ C8orf4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576196

Catalog No. PIPA576196

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

Specifications

• Antigen: C8orf4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tcim
• Gene Alias: 1110065B09Rik; 1810011O10Rik; AW121743; AW321058; C8orf4; chromosome 8 open reading frame 4; human thyroid cancer 1; protein C8orf4; RIKEN cDNA 1810011O10 gene; TC1; TC-1; TCIM; Thyroid cancer protein 1; thyroid cancer-1; Transcriptional and immune response regulator; uncharacterized protein C8orf4 homolog
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56892, 69068
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9D915, Q9NR00
• Gene Symbols: Tcim
• Immunogen: Recombinant fusion protein of human C8orf4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG