C8orf4 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 262791AP150UL

Catalog No. 50-173-5289

Description

This gene encodes a small, monomeric, predomitly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological maligcies.

Specifications

• Antigen: C8orf4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C8orf4
• Gene Alias: C8orf4, hTC 1, TC 1, TC1, Thyroid cancer protein 1, Uncharacterized protein C8orf4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56892, 69068
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.35 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q9NR00
• Gene Symbols: C8orf4, Tcim
• Immunogen: C8orf4 Fusion Protein Ag23930
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG