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Invitrogen™ C9orf7 Polyclonal Antibody
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Catalog No. PA548854
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400 μL
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PA548854 400 μL
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Catalog No. PA548854 Supplier Invitrogen™ Supplier No. PA548854
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Description

Rabbit Polyclonal Antibody

Predicted to react with rat based on sequence homology.

Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling. In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin- mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphoocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process.
TRUSTED_SUSTAINABILITY

Specifications

Antigen C9orf7
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CACFD1
Gene Accession No. Q8BG21, Q9UGQ2
Gene Alias 5930434B04Rik; C9orf7; CACFD1; calcium channel flower domain containing 1; calcium channel flower domain-containing protein 1; Calcium channel flower homolog; D9S2135; FLOWER; likely ortholog of H. sapiens chromosome 9 open reading frame 7 (C9orf7); mFwe; PSEC0107; PSEC0248; RGD1311501; UNQ3071/PRO9903
Gene Symbols CACFD1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 123-151 amino acids from the C-terminal region of human C9orf7.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11094, 381356
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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