Invitrogen™ C9orf72 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554905

Catalog No. PIPA554905

Description

Immunogen sequence: YGLSIILPQT ELSFYLPLHR VCVDRLTHII RKGRIWMHKE RQENVQKIIL EGTERMEDQG QSIIPMLTGE VIPVMELLSS MKSHSVPEEI Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 94%.

C9orf72 may play a role in endosomal trafficking and autophagy. It is known to interact with HNRNPA1, HNRNPA2B1, UBQLN2, and small Rab GTPSases. C9orf72 localizes in the nucleus, cytoplasm, endosome, lysosome, and autophagosome. Mutations in this gene can result in frontotemporal dementia and/or amyotrophic lateral sclerosis.

Specifications

• Antigen: C9orf72
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C9orf72
• Gene Alias: 3110043O21Rik; AI840585; ALSFTD; C9orf72; chromosome 9 open reading frame 72; FTDALS; FTDALS1; Guanine nucleotide exchange C9orf72; Guanine nucleotide exchange C9orf72 homolog; protein C9orf72; protein C9orf72 homolog; RGD1359108; RIKEN cDNA 3110043O21 gene; similar to RIKEN cDNA 3110043O21
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 203228
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunohistochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96LT7
• Gene Symbols: C9orf72
• Immunogen: Recombinant protein corresponding to Human C9orf72. Recombinant protein control fragment (Product #RP-92992).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG