C9orf78 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-3691	100 μL

Catalog No. 50-198-3691 Supplier Bioss Supplier No. BS15342R

Description

Rabbit Polyclonal Antibody

MLH1 is a DNA mismatch repair protein. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.

Specifications

• Antigen: C9orf78
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: C9orf78
• Gene Accession No.: Q9NZ63
• Gene Alias: bA409K20.3; C9orf78; chromosome 9 open reading frame 78; HCA59; Hepatocellular carcinoma-associated antigen 59; HSPC220; RGD1305178; similar to Hypothetical protein MGC11690; Telomere length and silencing protein 1 homolog; uncharacterized protein C9orf78; uncharacterized protein C9orf78 homolog
• Gene Symbols: C9orf78
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human C9orf78.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51759
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG