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  6. CA19-9/Sialyl Lewis A Antibody (121SLE) - Azide and BSA Free, Novus Biologicals™

CA19-9/Sialyl Lewis A Antibody (121SLE) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. p-7078688 Shop All R&D Systems Products
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NB254349100 100 μg
NB254349200 200 μg
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Catalog No. NB254349100 Supplier Novus Biologicals Supplier No. NBP254349100UG
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Description

Mouse Monoclonal Antibody

CA19-9/Sialyl Lewis A Monoclonal specifically detects CA19-9/Sialyl Lewis A in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen CA19-9/Sialyl Lewisa
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 121SLE
Concentration 1 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5 - 1 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml
Formulation PBS with No Preservative
Host Species Mouse
Immunogen Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A+B- patient (0Le).
Molecular Weight of Antigen 400 kDa
Purification Method Tissue culture supernatant
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Target Species Human
Content And Storage Store at -20 to -80C. Avoid freeze-thaw cycles.
Form Supernatant
Isotype IgM κ
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