Invitrogen™ CABLES1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536236

Catalog No. PIPA536236

Description

This antibody detects endogenous protein at a molecular weight of 67 kDa. Purity is >95% by SDS-PAGE.

Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.

Specifications

• Antigen: CABLES1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CABLES1
• Gene Alias: CABL1; CABLES; CABLES1; cdk3-binding protein ik3-1; CDK5 and Abl enzyme substrate 1; CDK5 and ABL1 enzyme substrate 1; HsT2563; ik3-1; interactor with CDK3 1; interactor-1 with cdk3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 307585, 63955, 91768
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8TDN4, Q9ESJ1
• Gene Symbols: CABLES1
• Immunogen: Synthetic peptide corresponding to amino acids 550-600 of human Cables1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG