Invitrogen™ CABLES1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103206

Catalog No. PIPA5103206

Description

Antibody detects endogenous levels of total Ik3-1.

Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death.

Specifications

• Antigen: CABLES1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CABLES1
• Gene Alias: CABL1; CABLES; CABLES1; cdk3-binding protein ik3-1; CDK5 and Abl enzyme substrate 1; CDK5 and ABL1 enzyme substrate 1; HsT2563; ik3-1; interactor with CDK3 1; interactor-1 with cdk3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 63955, 91768
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8TDN4, Q9ESJ1
• Gene Symbols: CABLES1
• Immunogen: A synthesized peptide derived from human CABLES1(Accession Q8TDN4), corresponding to amino acid residues L568-P618.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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