Invitrogen™ CABP7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553423

Catalog No. PIPA553423

Description

Immunogen sequence: LEEIREAFKV FDRDGNGFIS KQELGTAMRS LGYMPNEVEL EVIIQRLDMD GDGQVDFEEF VTLLGPKLST SGIPEKFHGT DFDTVFWKCD MQKLTVDELK RLLYDTFCEH LSMKDIENII MTEEESHLGT AEECPVDVET CSNQQIRQTC Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Specifications

• Antigen: CABP7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CABP7
• Gene Alias: CABP7; calcium binding protein 7; calcium-binding protein 7; calcium-binding protein CaBP7; CALN2; calneuron 2; calneuron II; Calneuron-2; calneuron-II; rCaBP7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 164633
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86V35
• Gene Symbols: CABP7
• Immunogen: Recombinant protein corresponding to Human CABP7. Recombinant protein control fragment (Product #RP-91369).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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