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Invitrogen™ CaBP8 Monoclonal Antibody (2G2)
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Catalog No. PIMA522701
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Quantity:
100 μg
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Catalog No. Quantity
PIMA522701 100 μg
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Catalog No. PIMA522701 Supplier Invitrogen™ Supplier No. MA522701
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Description

Mouse Monoclonal Antibody

Peptide Sequence: EELDEIREAF RVLDRDGNGF ISKQELGMAM RSLGYMPSEV ELAIIMQRLD MDGDGQVDFD EFMTILGPKL V.

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CaBP8
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2G2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene CALN1
Gene Accession No. Q9BXU9
Gene Alias 9630012C17Rik; CABP8; calcium-binding protein 8; calcium-binding protein CABP8; CALN1; calneuron 1; calneuron I; Calneuron-1; calneuron-I; MNCb-0849
Gene Symbols CALN1
Host Species Mouse
Immunogen CALN1 (AAH20200, 36 a.a. ~ 106 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 83698
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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