Invitrogen™ CaBP8 Monoclonal Antibody (2G2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA522701

Catalog No. PIMA522701

Description

Peptide Sequence: EELDEIREAF RVLDRDGNGF ISKQELGMAM RSLGYMPSEV ELAIIMQRLD MDGDGQVDFD EFMTILGPKL V.

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Specifications

• Antigen: CaBP8
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9BXU9
• Gene Symbols: CALN1
• Immunogen: CALN1 (AAH20200, 36 a.a. ~ 106 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 2G2
• Conjugate: Unconjugated
• Gene: CALN1
• Gene Alias: 9630012C17Rik; CABP8; calcium-binding protein 8; calcium-binding protein CABP8; CALN1; calneuron 1; calneuron I; Calneuron-1; calneuron-I; MNCb-0849
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 83698
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid