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Invitrogen™ CaBP8 Polyclonal Antibody
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Catalog No. PIPA5100419
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100 μL
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PIPA5100419 100 μL
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Catalog No. PIPA5100419 Supplier Invitrogen™ Supplier No. PA5100419
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CALN1.

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CaBP8
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CALN1
Gene Accession No. Q06BI3, Q9BXU9, Q9JJG7
Gene Alias 9630012C17Rik; CABP8; calcium-binding protein 8; calcium-binding protein CABP8; CALN1; calneuron 1; calneuron I; Calneuron-1; calneuron-I; MNCb-0849
Gene Symbols CALN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CALN1(Accession Q9BXU9), corresponding to amino acid residues M86-L136.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140904, 363909, 83698
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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