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CABYR Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501727915 Shop All Proteintech Group Inc Products
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50-172-7915 150 μL
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Catalog No. 50-172-7915 Supplier Proteintech Group Inc Supplier No. 123511AP150UL
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Description

Rabbit Polyclonal Antibody

Spermatozoa gain fertilization capacitation and hyperactivation after residing in the uterus or oviduct. Calcium, cAMP and protein tyrosine phosphorylation are necessary for the molecular mechanisms that allow for this transformation. CABYR (Calcium-binding tyrosine phosphorylation-regulated protein), also known as Fibrousheathin-2 or Cancer/testis antigen 88, is a 493 amino acid protein that is expressed in sperm flagella and exhibits increased tyrosine phosphorylation during capacitation. There are six named isoforms of CABYR that are produced as a result of alternative slicing events. Specifically, isoform 1 is expressed in the testis, while isoform 3 and isoform 5 are expressed in pancreas, brain and various brain tumors. Isoforms 1, 2 and 6 most likely bind calcium, whereas isoforms 3, 4 and 5 probably do not bind calcium.

Specifications

Antigen CABYR
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CABYR
Gene Accession No. O75952, Q9D424
Gene Alias CABYR, Calcium binding protein 86, Cancer/testis antigen 88, CBP86, CT88, Fibrousheathin 2, Fibrousheathin II, FSP 2, FSP2
Gene Symbols Cabyr
Host Species Rabbit
Immunogen CABYR Fusion Protein Ag3012
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26256, 71132
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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