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Invitrogen™ CACNA1I Polyclonal Antibody
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Catalog No. FEPA5144944
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FEPA5144944 100 μL
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Catalog No. FEPA5144944 Supplier Invitrogen™ Supplier No. PA5144944
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HHDKQEVQLA ETEAFSLNSD RSSSILLGDD LSLEDPTACP PGRKDSKGEL DPPEPMRVGD LGECFFPLSS TAVSPDPENF LCEMEEIPFN PVR Antigen sequence identity: Mouse 78%; Rat 26%.

CaV3.3 encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by CaV3.3 is characterized by a slower activation and inactivation compared to other T-type calcium channels. CaV3.3 may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants of CaV3.3. Voltage-gated calcium channels (CaV) are present in the membrane of most excitable cells and mediate calcium influx in response to depolarization, an proteins such as CaV3.3 regulate intracellular processes such as contraction, secretion, neurotransmission and gene expression. Diseases associated with CACNA1I include Childhood Absence Epilepsy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CACNA1I
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CACNA1I
Gene Accession No. Q9P0X4
Gene Alias Ca(v)3.3; CACNA1I; calcium channel, voltage-dependent, alpha 1I subunit; calcium channel, voltage-dependent, T type, alpha 1I subunit; calcium voltage-gated channel subunit alpha1 I; Cav3.3; CaVT.3; hypothetical gene supported by NM_020084; KIAA1120; low voltage-activated T-type calcium channel alpha-1 subunit (CACNA1I); low-voltage-activated calcium channel alpha13.3; RP1-172B20.4; voltage-dependent calcium channel; voltage-dependent T-type calcium channel subunit alpha-1I; Voltage-gated calcium channel subunit alpha Cav3.3
Gene Symbols CACNA1I
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 1842-1934. Recombinant protein control fragment (Product #RP-110066).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8911
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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