Invitrogen™ CACNA2D1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109474

Catalog No. PIPA5109474

Description

Immunogen sequence: DIKVEIRNKM IDGESGEKTF RTLVKSQDER YIDKGNRTYT WTPVNGTDYS LALVLPTYSF YYIKAKLEET ITQARSKKGK MKDSETLKPD NFEESGYTFI APRDYCNDLK ISDNNTEFLL NFNEFIDRKT PNNPSCNADL INRVLLDAGF TNELVQNYWS KQKNIKGVKA RFVVTDGGIT RVYPKEAGEN WQENPETYED SFYKRSLDND NYVFTAPYFN KSGPGAYESG IMVSKAVEIY IQGKLLKPAV V.

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Specifications

• Antigen: CACNA2D1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cacna2d1
• Gene Alias: Ca(v)alpha2delta1; Cacna2; Cacna2d1; CACNL2A; Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type); calcium channel, L type, alpha 2 polypeptide; calcium channel, voltage-dependent, alpha 2/delta subunit 1; calcium channel, voltage-dependent, alpha2/delta subunit 1; calcium voltage-gated channel auxiliary subunit alpha2delta 1; CCHL2A; CCHLA2; DHP; DHSCCA; dihydropryridine-sensitive calcium channel alpha-2 subunit; dihydropyridine-sensitive calcium channel alpha 2; dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit; H_DJ0560O14.1; LINC01112; lncRNA-N3; MHS3; unknown protein; voltage-dependent calcium channel alpha-2 delta subunit precursor; Voltage-dependent calcium channel subunit alpha-2/delta-1; Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1; Voltage-gated calcium channel subunit alpha-2/delta-1; WUGSC:H_DJ0560O14.1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12293, 781
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.99 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O08532, P54289
• Gene Symbols: Cacna2d1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human CACNA2D1 (NP_000713.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov