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Invitrogen™ CACNA2D4 Polyclonal Antibody
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Catalog No. PIPA588463
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100 μL
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PIPA588463 100 μL
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Catalog No. PIPA588463 Supplier Invitrogen™ Supplier No. PA588463
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AKSVFHHSHK HKKQDPLQPC DTEYPVFVYQ PAIREANGIV ECGPCQKVFV VQQIPNSNLL LLVTDPTCDC SIFPPVLQEA TEVKYNASVK CDRMRSQKLR RRPDSCHAFH PEENAQDCGG ASDT; Positive Samples: LO2, Raji; Cellular Location: Membrane, Single-pass type I membrane protein.

CACNA2D4 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CACNA2D4
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Cacna2d4
Gene Accession No. Q5RJF7, Q7Z3S7
Gene Alias 5730412N02Rik; BE686333; Cacna2d4; calcium channel, voltage-dependent, alpha 2/delta subunit 4; calcium voltage-gated channel auxiliary subunit alpha2delta 4; LOW QUALITY PROTEIN: voltage-dependent calcium channel subunit alpha-2/delta-4; RCD4; RGD1562038; Voltage-dependent calcium channel subunit alpha-2/delta-4; Voltage-dependent calcium channel subunit alpha-2-4; Voltage-dependent calcium channel subunit delta-4; voltage-gated calcium channel alpha(2)delta-4 subunit; voltage-gated calcium channel subunit alpha-2/delta-4
Gene Symbols Cacna2d4
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 992-1115 of human CACNA2D4 (NP_7589524).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 319734, 93589
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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