Invitrogen™ CACNB2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590894

Catalog No. PIPA590894

Description

Immunogen sequence: ATSSLPLSPT LASNSQGSQG DQRTDRSAPI RSASQAEEEP SVEPVKKSQH RSSSSAPHHN HRSGTSRGLS RQETFDSETQ ESRDSAYVEP KEDYSHDHVD HYASHRDHNH RDETHGSSDH RHRESRHRSR DVDREQDHNE CNKQRSRHKS KDRYCEKDGE VISKKRNEAG EWNRDVYIRQ; Positive Samples: Mouse heart; Cellular Location: Cell membrane, Cytoplasmic side, Peripheral membrane protein, sarcolemma.

The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.

Specifications

• Antigen: CACNB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cacnb2
• Gene Alias: AW060387; brain calcium channel beta-subunit CaB2c (splice variant of the gene CaB2); CAB1; CAB2; Cacnb2; CACNLB1; Cacnlb2; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; calcium voltage-gated channel auxiliary subunit beta 2; cardiac calcium channel beta subunit; cardiac calcium channel beta-subunit CaB2a (splice variant of the gene CaB2; cardiac calcium channel beta-subunit CaB2b (splice variant of the gene CaB2); CAVB2; Cavbeta2; Cchb2; CCHLB1; lambert-Eaton myasthenic syndrome antigen B; L-type calcium channel beta subunit; L-type voltage-dependent calcium channel beta-2 subunit; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; voltage-dependent calcium channel beta2A subunit; voltage-dependent calcium channel beta2B subunit; voltage-dependent L-type calcium channel subunit beta-2; voltage-gated calcium channel beta2 subunit transcript variant X13
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116600, 12296, 783
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.64 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q08289, Q8CC27, Q8VGC3
• Gene Symbols: Cacnb2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 481-660 of human CACNB2 (NP_9638902).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG