Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA587564

Invitrogen™ CACNG1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA587564
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA587564 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA587564 Supplier Invitrogen™ Supplier No. PA587564
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: DHWAVLSPHM EHHNTTCEAA HFGLWRICTK RIPMDDSKTC GPITLPGEKN CSYFRHFNPG ESSEIFEFTT QKEYSISAAA I; Positive Samples: Mouse skeletal muscle, Mouse liver, Mouse kidney, Rat skeletal muscle, Rat liver, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein.

Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an alpha1 subunit, a beta subunit, a gamma subunit and an alpha2 delta subunit. The beta subunit is encoded by four genes, designated beta1-beta4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the alpha1 subunit. L-type Ca ++ CP gamma1, also known as CACNLG or CACNG1, is a 222 amino acid multi-pass membrane protein belonging to the PMP-22/EMP/MP20 family. Expressed in skeletal muscle, L-type Ca ++ CP gamma1 is a subunit of the dihydropyridine (DHP) sensitive calcium channel and may play a role in excitation-contraction coupling. L-type Ca++ CP gamma1 is considered a novel marker for malignant hyperthermia susceptibility (MHS), an autosomal dominant disorder of skeletal muscle which manifests as a life-threatening hypermetabolic crisis triggered by commonly used inhalation anesthetics and depolarizing muscle relaxants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CACNG1
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.58 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cacng1
Gene Accession No. O70578, P97707
Gene Alias Cacng; Cacng1; CACNLG; calcium channel, voltage-dependent, gamma subunit 1; calcium voltage-gated channel auxiliary subunit gamma 1; dihydropyridine receptor gamma 1; dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma; L-type calcium channel gamma polypeptide; neuronal dihydropyridine-sensitive calcium channel gamma subunit; voltage-dependent calcium channel gamma-1 subunit
Gene Symbols Cacng1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12299, 29658
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.