Invitrogen™ CACNG2/4/8 Monoclonal Antibody (N245/36), PE

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545587

Catalog No. PIMA545587

Description

1 μg/mL of MA5-45587 was sufficient for detection of TARP Gamma2/4/8 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 35-55kDa. Does not cross-react with TARPGamma3. This antibody was formerly sold as clone S245-36.

Voltage-dependent calcium channel gamma-2 subunit, TARPGamma2 or Stargazin is encoded by the gene CACNG2 and is the transmembrane gamma subunit of the L-type calcium channel. Stargazin is in involved in regulation and trafficking of the ligand gated ion channel AMPA receptors. It is thought to play a role in learning and memory. Diseases associated with this gene include forms of deafness, Mental Retardation and childhood absnce epilepsy.

Specifications

• Antigen: CACNG2/4/8
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: O88602, Q71RJ2, Q8VHW2, Q8VHW5, Q8VHW9, Q8WXS5, Q9JJV4, Q9UBN1, Q9Y698
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10369, 12300, 140725, 140729, 27092, 54377, 59283, 81905, 84347
• Content And Storage: 4°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Clone: N245/36
• Conjugate: PE
• Gene: Cacng8
• Gene Symbols: Cacng2, Cacng4, Cacng8
• Immunogen: Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

Safety and Handling

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