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Invitrogen™ CACTIN Polyclonal Antibody
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Catalog No. PIPA523500
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100 μg
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Catalog No. Quantity
PIPA523500 100 μg
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Catalog No. PIPA523500 Supplier Invitrogen™ Supplier No. PA523500
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Rabbit Polyclonal Antibody

Predicted to react with Bacteria, Mosquito, Mouse, Pufferfish, Rat, Wild Turkey, Zebrafish.

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CACTIN
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene CACTIN
Gene Accession No. Q8WUQ7
Gene Alias 2510012J08Rik; C19orf29; C20H19orf29; CACTIN; cactin, spliceosome C complex subunit; fSAPc; functional spliceosome-associated protein c; NY REN 24 antigen; NY-REN-24; NY-REN-24 antigen; renal carcinoma antigen NY-REN-24; RGD1563634
Gene Symbols CACTIN
Host Species Rabbit
Immunogen A portion of amino acid 460-510 of human Cactin.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100521180, 485055, 58509
Target Species Human, Canine, Monkey, Bovine, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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