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Invitrogen™ CACTIN Polyclonal Antibody
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Catalog No. PIPA560019
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100 μL
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PIPA560019 100 μL
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Catalog No. PIPA560019 Supplier Invitrogen™ Supplier No. PA560019
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SLDDYDAGRY SPRLLTAHEL PLDAHVLEPD EDLQRLQLSR QQLQVTGDAS ESAEDIFFRR AKEGMGQDEA QFSVEMPLTG Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CACTIN
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.9 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CACTIN
Gene Accession No. Q8WUQ7
Gene Alias 2510012J08Rik; C19orf29; C20H19orf29; CACTIN; cactin, spliceosome C complex subunit; fSAPc; functional spliceosome-associated protein c; NY REN 24 antigen; NY-REN-24; NY-REN-24 antigen; renal carcinoma antigen NY-REN-24; RGD1563634
Gene Symbols CACTIN
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CACTIN. Recombinant protein control fragment (Product #RP-98977).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58509
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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