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Cactin Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501564909
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50-156-4909 20 μL
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Catalog No. 50-156-4909 Supplier Bethyl Laboratories, Inc Supplier No. A303349AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.

Specifications

Antigen Cactin
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CACTIN
Gene Accession No. Q8WUQ7
Gene Alias NY-REN-24, cactin, fSAPc, NY REN 24 antigen, NY-REN-24 antigen, cactin homolog, functional spliceosome-associated protein c, renal carcinoma antigen NY-REN-24, uncharacterized protein C19orf29
Gene Symbols CACTIN
Host Species Rabbit
Immunogen Between 75 and 125
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58509
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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