Cactin Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A303350AT

Catalog No. 50-156-4911

Description

The recommended shelf life for this product is 1 year from date of receipt.

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.

Specifications

• Antigen: Cactin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CACTIN
• Gene Alias: NY-REN-24, cactin, fSAPc, NY REN 24 antigen, NY-REN-24 antigen, cactin homolog, functional spliceosome-associated protein c, renal carcinoma antigen NY-REN-24, uncharacterized protein C19orf29
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58509
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q8WUQ7
• Gene Symbols: CACTIN
• Immunogen: Between 475 and 525
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG