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Invitrogen™ CAD Polyclonal Antibody
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Catalog No. PIPA597015
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100 μL
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PIPA597015 100 μL
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Catalog No. PIPA597015 Supplier Invitrogen™ Supplier No. PA597015
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LERLGPGKGE VRPELGSRQD VEALWENMAV IDCFASDHAP HTLEEKCGSR PPPGFPGLET MLPLLLTAVS EGRLSLDDLL QRLHHNPRRI FHLPPQEDTY VEVDLEHEWT IPSHMPFSKA HWTPFEGQKV KGTVRRVVLR GEVAYIDGQV LVPPGYGQDV RKWPQGAVPQ LPPSAPATSE MTTTPERPRR GIPGLPDGRF HLPPRIHRAS DPGLPAEEPK EKSSRKVAEP ELMGTPDGTC YPPPPVPRQA S; Positive Samples: SW620, HepG2, HeLa, HL-60; Cellular Location: Cytoplasm, Nucleus.

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CAD
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CAD
Gene Accession No. B2RQC6, P27708
Gene Alias 2410008J01Rik; 38E.19; anon-WO2004063362.83; Aspartate carbamoyltransferase; AU018859; cad; CAD protein; CAD trifunctional protein; cad-PA; cad-PB; cad-PC; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; carbamyl phosphatate synthetase 2; caudal; cb456; cd; CDG1Z; CG1759; CG1759-PA; CG1759-PB; CG1759-PC; Cpad; Dihydroorotase; Dmel\CG1759; Dmel_CG1759; Glutamine-dependent carbamoyl-phosphate synthase; Homeotic protein caudal; LD29596p; multifunctional protein CAD; S67; si:dkey-221h15.3; wu:fc30c12; wu:fc33d01; wu:fc67g02
Gene Symbols CAD
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1650-1900 of human CAD (NP_0043322).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24240, 69719, 790
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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