Invitrogen™ CAD Recombinant Rabbit Monoclonal Antibody (0O8D6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542883

Catalog No. PIMA542883

Description

Positive test controls include: 293T. Immunogen sequence: MAALVLEDGS VLRGQPFGAA VSTAGEVVFQ TGMVGYPEAL TDPSYKAQIL VLTYPLIGNY GIPPDEMDEF GLCKWFESSG IHVAALVVGE CCPTPSHWSA.

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

Specifications

• Antigen: CAD
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: B2RQC6, P27708
• Gene Symbols: CAD
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAD (P27708).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 0O8D6
• Conjugate: Unconjugated
• Gene: CAD
• Gene Alias: 2410008J01Rik; 38E.19; anon-WO2004063362.83; Aspartate carbamoyltransferase; AU018859; cad; CAD protein; CAD trifunctional protein; cad-PA; cad-PB; cad-PC; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; carbamyl phosphatate synthetase 2; caudal; cb456; cd; CDG1Z; CG1759; CG1759-PA; CG1759-PB; CG1759-PC; Cpad; Dihydroorotase; Dmel\CG1759; Dmel_CG1759; Glutamine-dependent carbamoyl-phosphate synthase; Homeotic protein caudal; LD29596p; multifunctional protein CAD; S67; si:dkey-221h15.3; wu:fc30c12; wu:fc33d01; wu:fc67g02
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 69719, 790
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid