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Cadherin-16 Antibody (CDH16/1071) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. p-7105733 Shop All R&D Systems Products
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NBP247745A 0.1 mg
NBP247745B 0.2 mg
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Catalog No. NBP247745A Supplier Novus Biologicals Supplier No. NBP2477450.1MG
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Mouse Monoclonal Antibody

Cadherin-16 Monoclonal specifically detects Cadherin-16 in Human, Mouse, Rat, Canine, Rabbit samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, CyTOF-ready.

Specifications

Antigen Cadherin-16
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Classification Monoclonal
Clone CDH16/1071
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin
Gene Symbols CDH16
Host Species Mouse
Immunogen Recombinant human CDH16 protein
Molecular Weight of Antigen 130 kDa
Purification Method Protein A or G purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1014
Test Specificity This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Target Species Human, Mouse, Rat, Canine, Rabbit
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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