Cadherin-18 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 130911AP150UL

Catalog No. 50-172-8481

Description

This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Specifications

• Antigen: Cadherin-18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH18
• Gene Alias: cadherin 18, type 2, Cadherin-14, Cadherin-18, CDH14, CDH14L, CDH18, EY CADHERIN
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1016
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13634
• Gene Symbols: CDH18
• Immunogen: Cadherin-18 Fusion Protein Ag3675
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG