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MilliporeSigma™ Calbiochem™ Calphostin C, Cladosporium cladosporioides
A cell permeable, highly specific inhibitor of protein kinase C (IC50 = 50nM) that interacts with the protein's regulatory domain by competing at the binding site of diacylglycerol and phorbol esters.
$279.00
Specifications
Color | Light Brown |
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Description | 95% by HPLC |
Target Proteins | PKC |
CAS | 121263-19-2 |
Molecular Formula | C44H38O14 |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
20-872-5100UG
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MilliporeSigma™
208725100UG |
100 μg |
Each for $279.00
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20-872-550UG
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MilliporeSigma™
20872550UG |
50 μg | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | |||||
Description
A cell permeable, highly specific inhibitor of protein kinase C (IC50 = 50nM) that interacts with the protein’s regulatory domain by competing at the binding site of diacylglycerol and phorbol esters. Does not compete with Ca2+ or phospholipids. At higher concentrations inhibits myosin light chain kinase (IC50 > 5μM), protein kinase A (IC50 > 50μM), protein kinase G (IC50 > 25μM), and p60v- src (IC50 > 50μM). Induces apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells. Requires brief exposure to light for activation.Specifications
Light Brown | |
PKC | |
C44H38O14 | |
DMSO or EtOH | |
Lyophilized |
95% by HPLC | |
121263-19-2 | |
790.8g/mol | |
Protect from light |
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