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MilliporeSigma™ Calbiochem™ AMN082 Dihydrochloride

Catalog No. 5047450001
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10mg

Description

A potent, selective and systemically active positive allosteric modulator for mGlu7 receptor (EC50 = 64-2

A potent, selective and systemically active positive allosteric modulator for mGlu7 receptor (EC50 = 64-290nM). One of the most frequently used agent for assessing the functional roles of mGlu7 receptors in a variety of brain functions (i.e. sleep pattern, learning and memory, and locomotion) and disorders (i.e. depression, anxiety, and Parkinsons disease). Induces internalization of mGlu7 receptors. Also acts on NMDA, AMPA, 5-HT receptors and norepinephrine transporter.
TRUSTED_SUSTAINABILITY

Specifications

Color White
Description 98% by HPLC
Target Proteins mGlu7 receptors
Molecular Formula C28H28N2·2HCl
Solubility DMSO
Content And Storage Protect from light
Form Solid
Quantity 10 mg
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