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MilliporeSigma™ Calbiochem™ AMN082 Dihydrochloride

A potent, selective and systemically active positive allosteric modulator for mGlu7 receptor (EC50 = 64-2

Manufacturer:  MilliporeSigma™ 5.04745.0001

Catalog No. 50-474-50001


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Description

Description

A potent, selective and systemically active positive allosteric modulator for mGlu7 receptor (EC50 = 64-290nM). One of the most frequently used agent for assessing the functional roles of mGlu7 receptors in a variety of brain functions (i.e. sleep pattern, learning and memory, and locomotion) and disorders (i.e. depression, anxiety, and Parkinsons disease). Induces internalization of mGlu7 receptors. Also acts on NMDA, AMPA, 5-HT receptors and norepinephrine transporter.
Specifications

Specifications

98% by HPLC
Protect from Light
mGlu7 receptors
DMSO
White solid
10mg
C28H28N2·2HCl
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