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MilliporeSigma™ Calbiochem™ InSolution™ HIF-1 Inhibitor

Catalog No. 4000925MG
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Quantity:
5 mg

Description

A cell-permeable amidophenolic compound that inhibits hypoxia-induced HIF-1 transcription activity (IC50

A cell-permeable amidophenolic compound that inhibits hypoxia-induced HIF-1 transcription activity (IC50 = 0.7 and 2.6μM using AGS and Hep3B cells, respectively, in a reporter assay) by selectively blocking the hypoxia-induced accumulation of cellular HIF-1α protein, while exhibiting no apparent effect on the cellular level of HIF-1α mRNA or that of HIF-1β protein.
TRUSTED_SUSTAINABILITY

Specifications

Formulation A 25 mM (5mg/459μL) solution of HIF-1 Inhibitor in DMSO.
Description 95% by HPLC
Target Proteins HIF-1
CAS 934593-90-5
Molecular Formula C26H29NO5
Formula Weight 435.5g/mol
Content And Storage Avoid Freeze-Thaw Cycles, Hygroscopic, Protect from Light
Form Liquid
Quantity 5 mg
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