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Calcein AM Solution, Sigma-Aldrich

Catalog No. 01259012 Shop All MilliporeSigma Supelco Products
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01-259-012 100 μL
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Catalog No. 01-259-012 Supplier MilliporeSigma Supelco Supplier No. C1359100UL
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Description

Calcein AM is a membrane permeable nonfluorescent molecule. It is converted to fluorescent calcein by intracellular esterases. Calcein has limited membrane permeability. Calcein AM is also a substrate for p-glycoprotein (Pgp). Presence of Pgp results in efflux of calcein AM and thereby decreases cellular fluorescence. On the other hand, presence of Pgp inhibitor increases cellular entry of calcein AM and thereby increases cellular fluorescence. Calcein AM plays an important role in early drug discovery.

TRUSTED_SUSTAINABILITY

Specifications

Concentration 4 mM
Product Type Stain
Quantity 100 μL
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