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Invitrogen™ Calcitonin Receptor Monoclonal Antibody (31/01-1H10-4-1-14)
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Catalog No. PIMA528094
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100 μg
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Catalog No. Quantity
PIMA528094 100 μg
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Catalog No. PIMA528094 Supplier Invitrogen™ Supplier No. MA528094
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Description

Mouse Monoclonal Antibody

Mouse anti Human calcitonin recptor antibody, clone 31/01-1H10-4-1-14 recognizes the human calcitonin receptor, a membrane protein with seven transmembrane domains that is coupled to G protein messenger systems.

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calcitonin Receptor
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 31/01-1H10-4-1-14
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with <0.1% sodium azide
Gene CALCR
Gene Accession No. P30988
Gene Alias C1A/C1B; calcitonin receptor; CALCR; Clr; COPT1; CRT; CT receptor; CTR; CT-R; CTR1; hCTR1
Gene Symbols CALCR
Host Species Mouse
Immunogen Synthetic peptide, DIPIYICHQELRNEPANN, derived from the cytoplasmic domain of human calcitonin receptor.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 799
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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