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Calcitriol, Tocris Bioscience™

Catalog No. 255150U
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Quantity:
50 μg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Vitamin D receptor (VDR) agonist

Active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Displays calcemic actions; stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Exhibits antitumor activity; inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.

Chemical Identifiers

CAS 32222-06-3
Molecular Formula C27H44O3
Molecular Weight (g/mol) 416.65
MDL Number MFCD00867079,MFCD11656129
InChI Key GMRQFYUYWCNGIN-NKMMMXOESA-N
Synonym calcitriol, rocaltrol, calcijex, topitriol, 1alpha,25-dihydroxyvitamin d3, silkis, soltriol, 1alpha,25-dihydroxycholecalciferol, calcitriolum, dihydroxyvitamin d3
PubChem CID 5280453
ChEBI CHEBI:17823
IUPAC Name (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
SMILES C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C

Specifications

Quantity 50 μg
Formula Weight 416.64
Percent Purity >99%
Chemical Name or Material Calcitriol

Safety and Handling

Recommended Storage Desiccate at -20°C
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