Invitrogen™ CALCOCO2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA530367

Catalog No. PIPA530367

Description

Recommended positive controls: Raji, HepG2, HepG2 whole cell extract (untreated), HepG2 whole cell extract (3 μM Thapsigargin treatment for 12 hr), HepG2 whole cell extract (3 μM Thapsigargin treatment for 24 hr), Huh-7 (untreated), Huh-7 (3 μM Thapsigargin treatment for 12 hr), Huh-7 (3 μM Thapsigargin treatment for 24 hr). Predicted reactivity: Human (99%), Chimpanzee (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a subunit of nuclear domain 10 (ND10) bodies. ND10 bodies are nuclear domains appearing immunohistochemically as ten dots per nucleus. They are believed to be associated with the nuclear matrix on the basis of their resistance to nuclease digestion and salt extraction. ND10 proteins are removed from the nucleus by herpes simplex virus-1 infection and may have a role in viral life cycles.

Specifications

• Antigen: CALCOCO2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CALCOCO2
• Gene Alias: 2410154J16Rik; antigen nuclear dot 52 kDa protein; C77254; calcium binding and coiled-coil domain 2; calcium-binding and coiled-coil domain-containing protein 2; CALCOCO2; Ndp52; Ndp52l1; nuclear domain 10 protein 52; nuclear domain 10 protein 52 like 1; nuclear domain 10 protein NDP52; Nuclear dot protein 52; RGD1559974
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10241, 76815
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.57 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: A2A6M5, Q13137
• Gene Symbols: CALCOCO2
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 174 and 389 of Human CALCOCO2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG