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Calcyphosine 2/CAPS2 Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
SDP

Catalog No. 501981998
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50-198-1998 100 μL
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Catalog No. 50-198-1998 Supplier Bioss Supplier No. BS12163R
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Description

Rabbit Polyclonal Antibody

CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development.

Specifications

Antigen Calcyphosine 2/CAPS2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CADPS2
Gene Accession No. Q86UW7, Q8BYR5
Gene Alias A230044C21Rik; Ca++-dependent secretion activator 2; Ca2+ dependent secretion activator 2; Ca2+-dependent activator protein for secretion 2; Cadps2; calcium dependent secretion activator 2; Calcium-dependent activator protein for secretion 2; Calcium-dependent secretion activator 2; Caps2; CAPS-2; cerebellum postnatal development associated protein 2; Cpd2; KIAA1591; RGD1559440
Gene Symbols CADPS2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Calcyphosine 2/CAPS2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 312166, 320405, 93664
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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