Caldesmon, HMW Mouse anti-Human, Clone: SPM168, Abnova™

Catalog No.	Quantity
89-933-710	100 μg

Catalog No. 89-933-710 Supplier Abnova Corporation Supplier No. MAB13177

Description

Mouse monoclonal antibody raised against native human Caldesmon, HMW.

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Specifications

• Antigen: Caldesmon, HMW
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Classification: Monoclonal
• Clone: SPM168
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native human Caldesmon, HMW.
• Dilution: Flow Cytometry (0.5-1 ug/10⁶ cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
• Gene Alias: CDM/H-CAD/L-CAD/MGC21352/NAG22
• Gene Symbols: CALD1
• Host Species: Mouse
• Immunogen: Crude human uterus extract.
• Purification Method: Protein A/G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 800
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG1 κ