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Invitrogen™ CALHM1 Polyclonal Antibody
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Catalog No. PIPA520895
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100 μg
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Catalog No. Quantity
PIPA520895 100 μg
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Catalog No. PIPA520895 Supplier Invitrogen™ Supplier No. PA520895
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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat liver tissue lysate. PA5-20895 can be used with blocking peptide PEP-1009.

Alzheimers disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-beta (Abeta) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Abeta levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CALHM1
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Calhm1
Gene Accession No. D3Z291, Q8IU99
Gene Alias calcium homeostasis modulator 1; calcium homeostasis modulator protein 1; Calhm1; EG546729; Fam26c; family with sequence similarity 26, member C; Protein FAM26C; RGD1564891
Gene Symbols Calhm1
Host Species Rabbit
Immunogen A 17 amino acid peptide near the amino terminus of human CALHM1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 255022, 499367, 546729
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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