CALHM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-3699	Proteintech Group Inc 220421AP150UL	150 μL

Description

Alzheimers disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-beta (Abeta) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Abeta levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.

Specifications

• Antigen: CALHM1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: D3Z291, Q8IU99
• Gene ID (Entrez): 255022, 499367, 546729
• Immunogen: CALHM1 Fusion Protein Ag14938
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CALHM1

• Concentration: 0.61 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CALHM1, FAM26C, Protein FAM26C
• Gene Symbols: CALHM1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody