Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA582661

Invitrogen™ CALM Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA582661
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA582661 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA582661 Supplier Invitrogen™ Supplier No. PA582661
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: DIPDLSQAPS SLLDALEQHL ASLEGKKIKD STAASRATTL SNAVSSLAST GLSLTKVDER EKQAALEEEQ ARLKALKEQR L Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.

PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).
TRUSTED_SUSTAINABILITY

Specifications

Antigen CALM
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Picalm
Gene Accession No. O55012, Q13492, Q7M6Y3
Gene Alias CALM; Clathrin assembly lymphoid myeloid leukemia; clathrin assembly lymphoid myeloid leukemia protein; clathrin-assembly lymphoid leukemia protein; clathrin-assembly lymphoid myeloid leukemia protein; CLTH; fit1; fit-1; LAP; mKIAA4114; PAP180; phosphatidylinositol binding clathrin assembly protein; phosphatidylinositol-binding clathrin assembly protein; PICALM; rCALM
Gene Symbols Picalm
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human PICALM. Recombinant protein control fragment (Product #RP-92550).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 233489, 8301, 89816
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.