Invitrogen™ Calmodulin 3 Monoclonal Antibody (1E2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524385

Catalog No. PIMA524385

Description

Peptide Sequence: INEVDADGNG TIDFPEFLTM MARKMKDTDS EEEIREAFRV FDKDGNGYIS AAELRHVMTN LGEKLTDEEV DEMIREADID GDGQVNYEEF VQMMTAK.

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Specifications

• Antigen: Calmodulin 3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CALM3
• Gene Alias: Calm; CALM1; Calm2; Calm3; CALML2; calmodulin; calmodulin 1; Calmodulin 1 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); Calmodulin III; calmodulin-1; Calmodulin-2; Calmodulin-3; Cam; Cam1; CAM2; Cam3; CaMA; CAMB; Camc; CAMI; CaMII; CAMIII; CPVT4; DD132; epididymis secretory protein Li 72; HEL-S-72; LQT14; PHKD; PHKD3; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 3; R75142; RNCAMIII
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 808
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 1E2
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P0DP25
• Gene Symbols: CALM3
• Immunogen: CALM3 (NP_005175.2, 53 a.a. ~ 149 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ