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Invitrogen™ Calmodulin 3 Polyclonal Antibody
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Catalog No. PIPA529980
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100 μL
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PIPA529980 100 μL
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Catalog No. PIPA529980 Supplier Invitrogen™ Supplier No. PA529980
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Mouse brain. Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%), Guinea pig (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calmodulin 3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.48 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene CALM3
Gene Accession No. P0DP25, P0DP28, P0DP31
Gene Alias Calm; CALM1; Calm2; Calm3; CALML2; calmodulin; calmodulin 1; Calmodulin 1 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); Calmodulin III; calmodulin-1; Calmodulin-2; Calmodulin-3; Cam; Cam1; CAM2; Cam3; CaMA; CAMB; Camc; CAMI; CaMII; CAMIII; CPVT4; DD132; epididymis secretory protein Li 72; HEL-S-72; LQT14; PHKD; PHKD3; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 3; R75142; RNCAMIII
Gene Symbols CALM3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Calmodulin 3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12315, 24244, 808
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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