Invitrogen™ Calmodulin 3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589886

Catalog No. PIPA589886

Description

Positive Samples: Rat testis; Cellular Location: Cytoplasm, cytoskeleton, spindle, spindle pole Immunogen sequence: LGQNPTEAEL QDMINEVDAD GNGTIDFPEF LTMMARKMKD TDSEEEIREA FRVFDKDGNG YISAAELRHV MTNLGEKLTD EEVDEMIREA DIDGDGQVNY E.

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Specifications

• Antigen: Calmodulin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CALM3
• Gene Alias: Calm; CALM1; Calm2; Calm3; CALML2; calmodulin; calmodulin 1; Calmodulin 1 (phosphorylase kinase, delta); calmodulin 3; calmodulin 3 (phosphorylase kinase, delta); Calmodulin III; calmodulin-1; Calmodulin-2; Calmodulin-3; Cam; Cam1; CAM2; Cam3; CaMA; CAMB; Camc; CAMI; CaMII; CAMIII; CPVT4; DD132; epididymis secretory protein Li 72; HEL-S-72; LQT14; PHKD; PHKD3; phosphorylase kinase subunit delta; phosphorylase kinase, delta subunit; prepro-calmodulin 1; prepro-calmodulin 3; R75142; RNCAMIII
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12315, 24244, 808
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.43 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P0DP25, P0DP28, P0DP31
• Gene Symbols: CALM3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-140 of human CALM3 (NP_0051752).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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