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Calneuron 1/CABP8 Rabbit anti-Human∣Mouse∣Rat, Polyclonal, Bioss
SDP

Catalog No. 501981999
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100 μL
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50-198-1999 100 μL
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Catalog No. 50-198-1999 Supplier Bioss Supplier No. BS12164R
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Rabbit Polyclonal Antibody

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Specifications

Antigen Calneuron 1/CABP8
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CALN1
Gene Accession No. Q06BI3, Q9BXU9, Q9JJG7
Gene Alias 9630012C17Rik; CABP8; Calcium-binding protein 8; calcium-binding protein CABP8; CALN1; calneuron 1; Calneuron I; Calneuron-1; calneuron-I; MNCb-0849
Gene Symbols CALN1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Calneuron 1/CABP8.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140904, 363909, 83698
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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